食管癌切除术后吻合口瘘危险因素地Meta分析.pdf

摘要 关 键 词:食管癌；吻合口瘘；Meta-分析；危险因素 论文类型：研究类 选题来源:其他 II 万方数据 ABSTRACT ABSTRACT Objective: To evaluate the risk factors of esophageal anastomotic leakage(EAL), to further explore the factors related to the anastomosis ,to prev ent and reduce the incidence of anastomotic leakage have the vital significance. Methods: We included all studies which analyzed the risk factors of esophageal carcinoma(cancer )anastomotic leakage(fistula) .Through the following electronic database MEDLINE(1993 ～2014.07) 、EMBASE (1993 ～2014.07) 、Chinese Biomedical Literature Database(CBM1993～2014.07) 、China National Knowledge Infrastructure(CNKI1993 ～2014.07) 、Chinese Scientific Journal Database(1994 ～ 2014.07) 、Chinese Biomedical Journal Database(CMCC1993～2014.07) 、Wanfang database(1993～2014.07),etc. The Revman 5.0 and the Peto method were used for Meta-analyses. Results: According to the inclusion and exclusion criteria, included in the Meta - analysis with 24 references.The incidence rate was lower in the female patients than in the male ones, the combined OR and 95 ％confidence interval was 0.73 （0.54～ 1.00）, but there was no statistical significance between them(P=0.05). The incidence rate was higher in the patients over the age of 60 years old than in those younger,the combined OR and 95 ％confidence interval was 0.79 （0.56～1.10）, but there was no statistical significance between them(P ＞0.05). The incidence rate was higher in the