溶出度模式识别方法在全天麻胶囊中的应用.ppt

Click to edit Master title style Company Logo Click to edit Master title style Company Logo HPLC fingerprint combined with Self-reference method and Between-group method for pattern recognition of the dissolution of Tall gastrodia capsule溶出度模式识别方法在全天麻胶囊中的应用 Contents Introdutcion 1 Experiment 2 Results and disscussion 3 3 Summary 4 4 天麻是名贵的中药材，产地、采收时间等多种因素均对其质量有较大影响，因此名贵中药材的质量控制应引起研究者的重视。 Introduction Gastrodiae Rhizoma (Chinese name: Tianma) is the dried rhizomes of Gastrodia elata Blume (Orchidaceae) and extremely valuable Traditional Chinese Medicine (TCM). Due to its precious herbal and complicated multi-component the evaluation method for TCM preparation is very significant. Nowadays, with the development of modern pharmaceutical technology, it were crushed, sterilized and packaged into capsule as the Tall gastrodia capsule. Batch label manufacturer Lot. Gastrodin contentsa (mg/ per capsule) Capsule powder weight(g) 1 Shanghai SCOND Pharmaceutical Co., Ltd., Shanghai, China 121204 2.939 0.4998 2 Shanghai SCOND Pharmaceutical Co., Ltd., Shanghai, China 120301 3.012 0.5002 3 Shanghai SCOND Pharmaceutical Co., Ltd., Shanghai, China 130101 2.887 0.4974 4 Guzhou EAKAN Pharmaceutical Co., Ltd., Guizhou, China3.841 0.5011 5 Guzhou Shengshi Longfang Pharmaceutical Co., Ltd., Guizhou, China 120301 3.454 0.4995 6 Shanghai SCOND Pharmaceutical Co., Ltd., Shanghai, China 121102 3.919 0.5041 7 Guzhou EAKAN Pharmaceutical Co., Ltd., Guizhou, China3.661 0.4938 8 Guzhou Shengshi Longfang Pharmaceutical Co., Ltd., Guizhou, China 120702 5.185 0.4992 9 Guzhou EAKAN Pharmaceutical Co., Ltd., Guizhou, China3.051 0.5101 10 Guzhou Shengshi Longfang Pharmaceutical Co., Ltd., Guizhou, China 130105 3.553 0.4998 Introduction Introduction release evaluation of MCTCM pharmacodynamics assessment fuzzy evaluation method Limitation： Only terminal evaluation； Can not describe the whole release behavior of MCTCM 不能对全程动态释药过程表征；无法找到释药差异性的核心原因。 Limitation： O