IMR整个动物实验相关内容.ppt

* * * * 同一只猪，常规剂量120kV，120mAs--FBP算法（SD-FBP）, 低剂量80kV，120mAs—iDose4、IMR算法（LD-iDose4、LD-IMR） * * 影像医学部放射科 WWW. (我是医生) 影像医学部放射科 影像医学部放射科 影像医学部放射科 影像医学部放射科 影像医学部放射科 Assessment of knowledge-based iterative reconstruction in 256-slice coronary CT angiography performed at different tube energies: An animal study * * Objective To investigate the performance of a knowledge-based iterative reconstruction (iterative model reconstruction–IMR) compared to filtered back projection(FBP)and a hybrid iterative reconstruction technique (iDose4) from prospective axial ECG-gated coronary 256-slice spiral CT angiography in miniature pigs under different tube voltages * * Methods Animals Five healthy minipigs, consisting of four females and one male, aged 300-400 days, weighing 39.5±2.0kg (range, 37-42kg) Pre-examination preparation Lower and stabilize heart rate(HR ≤ 75 bpm) Esmolol Basal anesthesia Diazepam(0.4 mg/kg)+ Ketamine(10 mg/kg) Maintaining anesthesia propofol(10 mg/kg) * * Scanning scheme and parameters Machine: Brilliance iCT; Philips Healthcare Tube voatage:120 kVp (Group A), 100 kVp (Group B) and 80 kVp tube voltage (Group C) Tube current-time product：120mAs Detector collimation： 128mm×0.625 mm Gantry rotation speed： 0.27 s/rotation Thickness： 0.9mm, Increment： 0.45mm Contrast medium：Omnipaque (350 mgI/mL, 450mmgI/kg), 3.5 mL/s * * Image post-processing A1 (120 kVp, FBP), A2 (120 kVp, iDose4), A3 (120 kVp, IMR) B1 (100 kVp, FBP), B2 (100 kVp, iDose4), B3 (100 kVp, IMR) C1 (80 kVp, FBP), C2 (80 kVp, iDose4), C3 (80 kVp, IMR) * * Image quality evaluation Objective evaluation The mean signal intensity (SI) and image noise in the aortic root region SNR = SIaortic root/SD aortic root CNR= (SIaortic root-SIsacrospinal muscle) /SDaorticroot Subjective evaluation The coronary arteries of the minipigs were divided into nine segments 5-point scale: 1 = non-assessable, 2 = fair, 3 = acceptable, 4 = good, 5 = excellent * * Statistical analysis One-wa