P-ERK1 2,抗兔二抗 南京农业大学.pdf

YBBRC 26676 No. of Pages 6, Model 5G 7 May 2011 Biochemical and Biophysical Research Communications xxx (2011) xxx–xxx 1 Contents lists available at ScienceDirect Biochemical and Biophysical Research Communications journal homepage: www.else /locate/ybbrc 2 Lactobacillus acidophilus S-layer protein-mediated inhibition of Salmonella-induced 3 apoptosis in Caco-2 cells 4 Pengcheng Li, Yinyan Yin, Qinghua Yu, Qian Yang ⇑ 5 College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China 6 7 a r t i c l e i n f o a b s t r a c t 9 1 9 10 Article history: Surface layer (S-layer) proteins are crystalline arrays of proteinaceous subunits present as the outermost 20 11 Received 14 April 2011 component of the cell wall in several Lactobacillus species. The underlying mechanism for how S-layer 21 12 Available online xxxx proteins inhibit pathogen infections remains unclear. To gain insights into the mechanism of the antimi- 22 crobial activity of Lactobacillus S-layer proteins, we examined how Lactobacillus S-layer proteins impact 23 13 Keywords: Salmonella Typhimurium-induced apoptosis in vitro in Caco-2 human colon epithelial cells. When 24 14 Lactobacillus S-lay