学习与记忆-微观课件.ppt

The regulation of gene expression by CREB. CREB-2 functions as a repressor of gene expression. CREB-1, an activator of gene expression, can displace CREB-2. When CREB-1 is phosphorylated by protein kinase A (and other kinases), transcription can ensue. Thanks！ * * * * * * First, their dendrites extend only into the molecular layer, where they branch like a fan, flattened in one plane. Second, Purkinje cell axons synapse on neurons in the deep cerebellar nuclei, which are the major output cells of the cerebellum.Thus, Purkinje cells are in a powerful position to modify the output of the cere