111125肌肉的化学终版本.pptVIP

4 Regulatory protein— Caldesmon caldesmon (Cald): calmodulin+desmon Cald and smooth muscle contraction regulation 5 Regulatory protein — Calponin 6 SRF (serum response factor) Myocardin—SRF transcriptional coactivators Myocardin related transcriptional factor（MRTF） Rho signaling pathway and MRTFs nuclear translocation Opposing roles of myocardin and Ets factors in the control of SRF 1 Muscle fiber structure - under the light microscope shape：cylindrical （d=10-100μm L=1-40mm ） nucleus： multinucleated, ovoid （50-100个/mm), just under the sarcolemma sarcop