新议桔梗“引经报使”理论研究思路与方法.docVIP

临床中药 新议桔梗引经报使理论研究思路与方法 林彦君, 章津铭 [摘要]引经理论是中药药性理论的重要组成部分, 桔梗作为肺之舟楫, 广泛应用于传统复方方剂中。阐述桔梗引经作用在传统复方中的体现, 通过文献调研, 简要辨析桔梗引经作用的现代研究现状, 并深入剖析其现状的不足之处, 基于药物的体内主要作用环节, 提出桔梗引经报使理论的新思路, 以期将中药归经理论与现代靶向理论有机结合, 为揭示中药引经理论的作用机制提供可借鉴的研究模式。 [关键词]桔梗; 引经理论; 研究思路[中图分类号]R 2851 [文献标识码]A [文章编号]1674-926X(2011 02-0050-03 D iscussion on the r esear ch thoug h t and m ethod of the m er id ian gu i d ing theory of P la tycodon R oot/LINY an jun , Z HA NG J i n m in g ///(Pharma c y Colle ge , Che ngdu Univ ersity o f T rad itio na lCh i neseMe d ici ne ; TheM i n istry o f Educ a tion K e y Labora to ry o f St a n dard i za tio n o f Chinese H e rb a l M e dicine ; St a te Ke y Labo ra tory Bre e d in g Ba se o f Syste ma tic Researc h , D e velo p m e nt and Utiliz a tio n o f Ch i nese M e dicine Resources , Che ngdu 610075, China [A bstra ct]Med ici na l g u i de theory is an i m portant part of theor y of pr operty of Ch i nese materia med ica . Platycodo n Root , as a messenger drug leading into the l ung , isw ide l y used in the traditio nalCh i nese herba l f or mu las . A t first , the co mb i natio n of Platycodo n Root in the traditi ona l f or mu las accord i ng to its meri d ian g u i d i ng is descri bed . A nd t hen , via desk research /literature revie w , the research status of the meridian g u i d i ng f unctio n of Platycodo n Root is su mmed up , and the shortco m i ngs is ana l yzed . A t last , based o n the m ain acti o n of dr ugs i n bodies , a ne w tho ug ht is ra ised to study t he theor y of meridian guidi ng of Platycodo n Ro ot , i n order to co mbine the theory of meridian g u i d i ng of Chinese materia medica w ith the theory of m edic i ne targeting , and provides a ne w research style to revea l the mechan is m of m eridian guiding of Ch i nese m ateria m edica . [K ey words]P latyco do n Ro ot ; t heory of m eri d i an gu i d i ng ; research t ho ught [作者单位]成都中医药大学药学院中药材标准化教育部重 点实验室中药资源系统研究与开发利用省部共建国家重点实验室培育基地, 四川成都610075 [作者简介]林彦君( , 女, 硕士, 讲师, 主要从事中药新 制剂的开发与应用