促炎和抗炎因子在急性胰腺炎发病机制中的研究进展.docVIP

wcjd@ 世界华人消化杂志 2010年 6月 28日 ; 18(18: 1912-1918 ISSN 1009-3079 CN 14-1260/R 文献综述 REVIEW 促炎和抗炎因子在急性胰腺炎发病机制中的研究进展 徐毅晖, 陈 垦, 崔淑兰, 王 晖 徐毅晖, 陈垦, 广东药学院临床医学院内科学教研室 广东省 广州市 510310 崔淑兰, 广东药学院附属门诊部 广东省广州市 510224王晖, 广东药学院中药学院药理学教研室 广东省广州市 510006 广东省科学事业计划基金资助项目, No. 2007A060305007广东省科学事业计划基金资助项目, No. 2007B030702004广州市科学技术基金资助项目, No. 2007Z3-E5011 广东省自然科学基金资助项目, No. 8151022401000012作者贡献分布: 本文综述由徐毅晖完成; 由陈垦、崔淑兰及王晖 审校. 通讯作者: 陈垦, 主任医师, 510310, 广东省广州市, 广东药学院 临床医学院内科学教研室. chenkenck@126.com 电话: 020-3405585 收稿日期: 2010-03-25 修回日期: 2010-05-04 接受日期: 2010-05-10 在线出版日期: 2010-06-28 Advances in understanding the role of inflammatory and antiinflammatory factors in the pathogenesis of acute pancreatitis Yi-Hui Xu, Ken Chen, Shu-Lan Cui, Hui Wang Yi-Hui Xu, Ken Chen, Department of Internal Medicine, College of Clinical Medicine, Guangdong Pharmaceuti-cal University, Guangzhou 510310, Guangdong Province, China Shu-Lan Cui, Outpatient Department, Guangdong Pharma-ceutical University, Guangzhou 510024, Guangdong Prov-ince, China Hui Wang, Department of Pharmacology, College of Chi-nese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, Guangdong Province, China Supported by: the Scientific Research Program of Guang-dong Province, Nos. 2007A060305007 and 2007B03070 2004; the Science and Technology Foundation of Guang-zhou, No. 2007Z3-E5011; and the Natural Science Founda-tion of Guangdong Province, No. 8151022401000012 Correspondence to: Ken Chen, Department of Internal Medicine, College of Clinical Medicine, Guangdong Phar-maceutical University, Guangzhou 510310, Guangdong Province, China. chenkenck@126.com Received: 2010-03-25 Revised: 2010-05-04 Accepted: 2010-05-10 Published online: 2010-06-28 Abstract Acute pancreatitis (AP is a common clinical disorder presenting as acute abdomen. As AP is often complicated with many other serious diseases, the overall mortality rate is high in AP patients. At present, the research on the pathogenesis of AP has attracted wide attention though it h