cxg_003e(食品添加剂摄入量简单评估指南).pdf

1 CAC/GL 3-1989 Page 1 of 18 GUIDELINES FOR SIMPLE EVALUATION OF FOOD ADDITIVE INTAKE CAC/GL 03-1989 ________ CONTENTS 1. INTRODUCTION 2. BACKGROUND 2.1 Acceptable Daily Intake (ADI) 2.2 Theoretical Maximum Daily Intake (TMDI) 2.3 Estimated Daily Intake (EDI) 3. ACCEPTABLE DAILY INTAKE AND INTAKE ESTIMATES 4. DATA AVAILABLE 4.1 Food consumption and regulation of use of food additives 4.2 Approaches for determining food consumption data 5. SIMPLE APPROACH FOR THE EVALUATION OF FOOD ADDITIVE INTAKE 5.1 Additives for which an evaluation of intake would have to be done 5.2 Proposed method for a simple evaluation of the intake of an additive 6. SUMMARY ANNEX I - Example of calculation for benzoic acid ANNEX II - Example of calculation for sweeteners 2 CAC/GL 3-1989 Page 2 of 18 1. INTRODUCTION The first step in the permitted use of food additives is the examination of toxicological studies by the Joint Expert Committee on Food Additives (JECFA), the establishment of an Acceptable Daily Intake (ADI), and the elaboration of identity and purity criteria. In the second step, proposals for the permitted use of an additive in different foodstuffs are made by the responsible governmental agencies or by the Codex commodity committees to the Codex Committee on Food Additives and Contaminants (CCFAC). The endorsement of the proposed use in a