子宫癌UterineCancer妇科八年制教学.pptVIP

Stage IIa* Endocervical glandular involvement only Stage IIb* Cervical stromal invasion Stage IIIa* Tumor invades the serosa of the corpus uteri and/or adnexae and/or positive cytological findings Stage IIIb* Vaginal metastases Stage IIIc* Metastases to pelvic and/or para-aortic lymph nodes Stage IVa* Tumor invasion of bladder and/or bowel mucosa Stage IVb* Distant metastases, including intra-abdominal metastasis and/or inguinal lymph nodes Treatment ? Surgery Radiation ? Chemotherapy Hormone therapy ? Early stage --- surge+ postoperative adjuvant therapy ? Advanced stage --- radiation+ surge+ medicine Principle of choice ? General condition (Age, complication) ? Clinical stage ? Tumour pathologic type Surgery ? Object – Operative pathologic stage, finding prognosis risk factors – Remove uterus and metastasis tumour ? Stage I : – Abdorminal hysterectomy + bilateral salpingoophorectomy + selective lymphadenectomy – clear cell or papillary carcinoma – omentectomy+appenditectomy Uterine Cancer Xi-Shi Liu Obstetrics and Gynecology Hospital Fudan university 2007.04 General Description ? Uterine cancer is one of the most common malignancy of female genital tract. ? The incidence is increasing worldwide in recent years. ? Overall,2%-3% of women develop uterine cancer during their lifetime. General Description ? A malignant epithelial disease that occurs in endometrial gland of uterus ? Also called endometrial cancer Classification (pathogenetic,biologic behavior ) ? Estrogen dependent type - have a history of exposure to unopposed estrogen (either endogenous or exogenous). - Hyperplastic endometrium - Better differentiafed - ER(+),PR(+) - Mere favorable prognesis ? Estrogen independent type -- Have no source of estrogen stimulation of endometrium. --Arising in background of atrophic endemetrium --Less differentiated --ER(-)PR(-) --Poor prognosis Risk Factors 1. Medical conditions a. Diabetes mellitus