RicketsofVitaminDDeficiency维生素D缺乏性佝偻病 课件.pptVIP

Rickets of Vitamin D Deficiency 维生素 D 缺乏性佝偻病 Definition ? Rickets, a deformative disease that occurs among children, are characterized by deficient mineralization of the bone matrix （骨基质） as a result of deficiencies of calcium or phosphorus or both. ? Defective mineralization at the growth plate ? Osteomalacia （骨软化） at the corticoendosteal level Source and Metabolism of Vitamin D ? Animal food ： Vit D 3 ? Vegetal food: Vit D 2 ergosterin( 麦角固醇 ) ergocalciferol( 麦角骨化醇 ) Endogenic Vit D 3 —— main source Ectogenic Vit D —— from food intestine b