结节病的现代诊治[1]资料讲解.pptVIP

SACE produced by granuloma cells; Elevated in 60%(30%~80%) of sarcoid pts. （normal 17~34u/ml ); Not elevated in 30-40% of sarcoid pts.; Elevated in 5% of normals; Elevated in many diseases， nonspecific; Very elevated (4? normal): sarcoid and leprosy; No evidence that SACE reflects level of alveolitis，doesn’t relate to disease activity? Elevated ACE level Tuberculosis Atypical mycobacteria Leprosy Histoplasmosis Coccidioidomycosis Berylliosis Hodgkin’s disease Lung cancer Alcoholic liver disease Hyperthyroidism Diabetes mellitus Asthma Ann Clin Biochem 1989; 26:13-18 Panda sign: Upta