化学原料药多功能车间工艺设计.docVIP

PAGE PAGE II 摘 要 本设计以硫辛酸、依非韦伦、缬沙坦的相关论文提供的工艺为基础，我们根据三个产品的实验室工艺，结合中试放大技术，再进行车间工艺设计，从而将实验室研发产品转化为工业化产品。为了实现多功能规模化生产，我们进行了化学原料药车间工艺设计。 设计中首先对设计依据进行了说明，然后对产品进行了介绍，设计了工艺流程，绘制了带控制点的工艺流程图，再以设备为单位进行了物料衡算，列出了各设备的进出物料平衡表。以此为基础进行了热量衡算，确定了加热和冷却介质的用量。同时进行了设备选型计算，确定了各设备的生产能力和型号，绘制了非标准设备装配图，并根据所选的设备绘制了工艺设备安装的平面布置图，同时还绘制了管道布置图。在设计中，根据本车间的废物性质和排放量制定了“三废”的处理方法，同时制定了消防等安全防范制度，最后对生产情况进行了详细的劳动组织和人员安排。 关键词：硫辛酸；依非韦伦；缬沙坦；物料衡算；热量衡算；设备选型；多功能车间布置  Abstract This design by lipoic acid, whalen, valsartan related paper provides technology as the foundation, we according to the three products laboratory techniques, combined with the pilot amplification technology, process design for workshop, thus converting the laboratory research and development products to industrial products. In order to realize the multi-functional large-scale production, we conducted chemical API workshop process design. First design basis for the design of instructions, and then the product are introduced, the design process, draws the control points of process flow diagram, and then to equipment as a unit for the material balance, lists the various equipment in and out of the material balance. Based on the heat balance, the amount of heating and cooling medium was determined. While the equipment type selection calculation to determine the production capacity of each equipment and model, draw the non-standard equipment assembly drawing, and according to the selected equipment drawing the layout of process equipment installation, also draw the pipeline arrangement plan. In the design, according to the nature of the workshop of the waste and made the processing method of \three wastes\ emissions, at the same time made the fire safety prevention system, such as the last on the production situation of labor organization and personnel arrangement. Keywords：Lipoic acid; whalen; Valsartan; Material balance; Heat balance; Equipment selection; Multi-functional workshop layout 目录 TOC \o 1