欧洲低钠血症疗指南.pptVIP

2014欧洲 低钠血症诊疗指南解读  欧洲危重病学会(ES|CM) 欧洲内分泌学会(ESE) 欧洲肾脏最佳临床实践( European Renal Best Practice ERBP)为代表的欧洲肾脏病 协会和欧洲透析与移植协会(ERA-EDTA) 共同制定了欧洲低钠血症临床诊疗指南  低钠血症 Hyponatraemia, defined as a■定义: serum sodium concentration 135 mmol/ is the most 血清钠低于135 mmol/ l common disorder of body fluid and electrolyte balance encountered in clinical practice ■临床最常见的水盐失衡,其 It occurs in up to 30% of 发生率约占住院患者的30% hospitalised patients and c lead to a wide spectrum of clinical symptoms, from subtle 症状不一,从轻微到致命 to severe or even life threatening(10, 11)  6低钠血症诊断 Diagnosis of hyponatraemia 6.1.分类: Classification of hyponatraemia 6. 1. 1. Definition of hyponatraemia based on ■根据血钠浓度分类 biochemical severity 61 6.1.1.1 We define mild hyponatraemia as a biochemical 轻度(mld)低钠血症:血钠: sodium concentration between 130 and 135 mmo/ as measured by ion-specific 130~135mmol electrode 6. 1.1.2. We define moderate hyponatraemia as a bio. 6112: chemical finding of a serum sodium concentration between 125 and 129 mmo as measured by ion- 中度( moderate)低钠血症:血钠: specific electrode 125~129mmol 6.1.13. We define profound hyponatraemia as a bio chemical finding of a serum sodium concentration 125 mmoll as measured by ion-specific electrode 6113 重度( profound)低钠血症:血钠: 125mmo/  ■依据发生时间分类 6. 1. 2. Definition of hyponatraemia based on time of development ■6121 6.1.21. We define acutehypona traemia as hyponatraemia 急性低钠血症48h that is documented to exist 43h 6.1.2.2. We define chronic hyponatraemia as hyponatrae ia that is documented to exist for at least 48h 6.1.2.3. If hyponatraemia cannot be dassified, we consider it ■慢性低钠血症≥48h being chronic unless there is cinical or anamnestic evidence of the contrary (Table B). 6123 如果不能对其分类,除非有临 床或回顾性反证(表8),则应 认为系慢性低钠血症  6. 13. Definition of hyponatraemia based on 根据症状分类: 6.1.3.1. We moderately symptomatic hyponatraemia 6131:中度症状 as amy biochemical degree of hyponatraemia in the presence of moderately severe sympto