口腔学英文课件：SKIN TUMORS.pptVIP

MALIGNANT MELANOMA Predisposition-UVR ,xeroderma pigmentosa,displastic nevus syndrome,congenital melanocytic nevi Clinical features Preceded by a superficial and radial growth phase, shown clinically as the expansion of an irregularly pigmented macule or plaque Most are multicolored mixtures of black, brown, blue and pink. Margins are irregular with reniform projections and notches Malignant cells are at first are usually confined to the epidermis and uppermost dermis Later they invade more deeply and may metastasize Hallmarks of a malignant melanoma with its asymmetry, irregular borders an