神经精神药理英文课件：Animal Model in psychiatry.pptVIP

There is no difference in saccharin and nicotine preference or consumption based on genotype Increased alcohol consumption Sensitivity Behavioral Disinhibition Anxiety,Risk taking gPKC Mutation leads to reduced anxiety or increased risk taking Mutation leads to reduced sensitivity Mutation leads to increased impulsivity Conclusions about g-PKC g-PKC mutation has pleiotropic effects on phenotypes that may predispose individuals to greater risk of alcohol abuse Translating these results to humans Are there human polymorphisms in the g-PKC gene? Are they