水产药理学期末论文-秀才青鱼.pdfVIP

目录 1 抗菌渔药药动学相关综述 摘要:近些年我国水产养殖业发展迅猛，水产品总产量逐年增长， 但在养殖生产过程中的疾病给养殖业带来了重大 经济损失。为了防 治疾病，在抗菌渔药使用中又出现了滥用、错用和不规范使用等现象， 影响了我国水产养殖业的可持续发展。目前关于水产动物 药动学及 残留规律等研究较少。本文综述了近年来有关抗菌渔药资料，阐述了 水产动物体内抗菌渔药 药动学及药物残留特征 检测方法和研究 进展，以期为水产养殖业健康发展提供参考。 关键词 ：抗菌药；渔药；药动学 Review on pharmacokinetics of antibacterial Abstract: In recent years, the aquaculture industry in our country has developed rapidly, the total output of aquatic products has been increasing year by year. But the disease in the process of aquaculture has 2 brought great economic losses to the aquaculture industry. In order to prevent and cure diseases, the phenomena of abuse, misuse and non-standard use in the use of antimicrobial fishery have also affected the sustainable development of aquaculture in China. At present, there are few studies on the pharmacokinetics and residue of aquatic animals. In this paper, the information of antimicrobial fishery in recent years was reviewed, and the methods and research progress of pharmacokinetic and drug residue characteristics of aquatic animals were described in order to provide reference for the healthy development of aquaculture. Key words: antimicrobials; fishery drugs; pharmacokinetics 近年来，因违规用药导致药物残留、进而引发的水产品质量安全 问题引起人们的普遍关注。抗菌类药物因其抗菌谱广、抗菌力强、易 吸收和半衰期长等特点广泛被应用于水产养殖病害防治。药物代谢动 力学定量研究药物在生物体内吸收、分布、排泄和代谢规律，随着细 胞生物学和分子生物学 发展，在药物体内代谢物及代谢机理研究已 经有了长足 发展。通过药物在体内代谢产物和代谢机理研究，可以 发现生物活性更高、更安全的新药。了解抗菌类渔药 药动学作用对 实践中渔药 选择具有指导意义。本文综述了近年来有关抗菌渔药药 动学相关，阐述了水产动物体内抗菌渔药 药动学及药物残留特征 检测方法和研究进展。