甲泼尼龙琥珀酸钠辅助治疗儿童重症肺炎支原体肺炎的疗效评价.docxVIP

甲泼尼龙琥珀酸钠辅助治疗儿童重症肺炎支原体肺炎的疗效评价 周婷 [摘要] 目的 探討甲泼尼龙琥珀酸钠在儿童重症肺炎支原体肺炎（MPP）辅助治疗中的效果。 方法 选择北京市昌平区医院20XX年9月～20XX年12月收治的重症肺炎支原体肺炎患儿80例，采用随机分配方法分为观察组和对照组各40例。两组均给予阿奇霉素序贯治疗和常规吸痰、雾化对症治疗，观察组加甲泼尼龙琥珀酸钠静脉滴注治疗，对比两组患儿退热时间、住院时间、肺功能、治疗总有效率。 结果 观察组治疗总有效率高于对照组，差异有统计学意义（P0.01）。观察组患儿治疗后肺功能较治疗前有明显改善，差异有统计学意义（P0.01）。观察组退热时间、肺部阴影消失时间和住院时间均少于对照组，差异有统计学意义（P0.05）。 结论 临床使用甲泼尼龙琥珀酸钠辅助治疗重症肺炎支原体肺炎，可以有效减轻临床症状、缩短病程，并减轻气道炎性反应，有利于小气道功能恢复，改善肺功能，提高临床的治愈率。 [关键词] 重症;肺炎支原体肺炎;甲泼尼龙琥珀酸钠;肺功能 [中图分类号] R725.6 [文献标识码] B [文章编号] 1673-9701（2020）21-0075-03 Evaluation of the efficacy of methylprednisolone sodium succinate in the treatment of severe mycoplasma pneumoniae pneumonia in children ZHOU Ting Department of Pediatrics， Beijing Changping District Hospital， Beijing 102200， China [Abstract] Objective To investigate the effect of methylprednisolone sodium succinate in the adjuvant treatment of severe mycoplasma pneumoniae pneumonia（MPP） in children. Methods Eighty children with severe mycoplasma pneumoniae pneumonia admitted to Beijing Changping District Hospital from September 20XX to December 20XX were selected， and randomly divided into observation group and control group 40 cases. Both groups were given azithromycin sequential treatment and conventional sputum suction and atomization symptomatic treatment. The observation group was also treated with methylprednisolone sodium succinate for intravenous drip infusion. The statistical differences in fever withdrawal time， hospital stay， lung function， and total effective rate between two groups were compared. Results The total effective rate of treatment in the observation group was higher than that in the control group， and the difference was statistically significant（P0.01）. The children in the observation group had significantly improved lung function after treatment compared with before treatment， and the difference was statistically significant（P0.01）. The fever withdrawal time， disappearance time of lung shadow，