复方乌骨藤汤联合化疗治疗晚期非小细胞肺癌的临床研究.docVIP

复方乌骨藤汤联合化疗治疗晚期非小细胞肺癌的临床研究 张炳谦、闵天劳、伍千国 （杨凌高新医院，陕西杨凌712100） 【摘要】 目的 观察和评价复方乌骨藤汤联合化疗治疗晚期非小细胞肺癌的临床疗效和毒副反应。方法 选择非小 细胞肺癌（热毒壅肺，痰瘀互结，气虚血瘀证）患者108例，分为复方乌骨藤汤联仑化疗组38例（治疗组）、 单纯化疗组36例（对照1组）及单纯复方乌骨藤汤组34例（对照2组），两组化疗均采用NP方案，完成 2个周期后进行疗效评价。 结果 治疗组有效率为73.7%,对照1组有效率为41.7%,对照2组有效率为47. 1%,治疗组分别同两对照 组比较皆有显箸性差异（卩0.05）,两对照组比较无显著性差异（P0.05）,治疗组在中医分型疗效分 析、体靈变化及生活质最等方面疗效均明显优于对照1组（P值均0.05）,治疗组同对照2组均无显著 差异（P值均 0. 05）:治疗组同对照2组NK细胞活性及CD1 / CD8比值治疗后明显髙于治疗前（P值均 0.01）。治疗组及对照2组毒副反应发生率明显低于对照1组（P值均 0. 05） o 结论复方乌骨藤汤联合化疗治疗晚期非小细胞肺癌（热毒壅肺，痰瘀互结，气虚血瘀证）有较好疗效,能 有效改善临床症状，提高免疫功能，能明显提高复方耳骨藤汤的治疗效果，并对化疗药物有明显的增效减 毒作用。 【关键词】 复方乌骨藤汤：化疗；晚期菲小细胞肺癌 The clinical study on therapeutic effects of prescription crow bone soup combined with chemotherapy to late non-small cells lung cancer Zhang Bing-qian, Mian Tian-lao, Wu Qian-guo （Yangling high-tech hospital, shaanxi yangling, 712100） Abstract Purpose: The clinical effect and side-effects of prescription crow bone soup combined with chemotherapy to late non-small cells lung cancer were observed and evaluated? Method: 108 non-smal1 cells lung cancer case were selected? The prescription crow bone soup combined with chemotherapy group was 38 cases （treatment group）?The single chemotherapy group was 36 cases （control group 1）? The single prescription crow bone soup group was 36 cases （control group 2）. Two chemotherapy groups were completed through NP ways and the effects were evaluated after two weeks? Results: The curative ratio of treatment group was 73.7%. The curative ratio of control group and control group 2 were 41. 7%. There was a significant difference between treatment group and two control groups （p0? 05）, but two control groups had no significant difference （P0.05）? About the traditional Chinese physician non-single types analysis, body weight change and quality of life, the treatment group surpass the control group 1 （p0? 05）, but there was no significant difference as compared with control group 2 （P0. 05）? The treatment group with the control group NK cell activity a