c反应蛋白水平变化在急性呼吸窘迫综合征患者预后判断中的意义.docxVIP

·406· 蝤鏖内抖苤壶垫!Q生鱼月筮塑鲞箜鱼翅』垦丛坠堕丛鱼：血塑垫!Q：坠!：至2：№：垒 ·论著· C反应蛋白水平变化在急性呼吸窘迫综合征患者预后判断中的意义 槐永军张绍敏马壮陈萍 [中图分类号]11563．8 [文献标识码]A 【DOI]10．3969／j．issn．1001-9057．2010．06．015 [摘要] 目的探讨C反应蛋白(CRP)指标变化在急性呼吸窘迫综合征(AnDS)患者预后判断中的意义。方法收集我院呼吸内科重症监护室30例ARDS患者临床资料，根据患者临床预后分为死亡组及存活组，比较患者CRP变化在临床预后判断中的价值。结果30例患者中，死亡20 例，存活10例。死亡组与存活组患者的CRP基础值(确诊时)比较差异无显著性(P0．05)。存活组ClIP治疗后较治疗前均降低，死亡组3例降低，17例升高。两组治疗后CRP比较差异显著(P 0．01)。两组治疗前后CRP指标比较差异显著(P0．01)。治疗后CRP降低患者的病死率 (23．1％，3／13)明显低于CRP升高患者的病死率(100％，17／17，P0．01)。结论动态监测CRP水平的变化对判断ARDS患者的预后具有较为重要的指导意义。 [关键词] 急性呼吸窘迫综合征；C反应蛋白；预后 ’nIe role of CRP in amessing prognosis of the acute respiratory distres6 syndrome日叽¨ Yon∥un，zHANG SHaomin。MA Zhuang．et a1．Depanmem of Respiratory Medicine．tk General Hospital of Shengyang Military Region．Shengyang 110016，China [Abstract]0bjective To discuss the role of cRP in assessing the prognosis of patients with the respiratorydistresssyndrome(ARDS)．Methotis30of ARDSpatientsadmitted in the de-partment of respiratory intensive unit(RICU)of the General Hospital of Shenyang Military ne60n coHected andanalyzed．Accordingthe clinicalprognosisthepatientsdivided into deathandsurvival group．The effects of CRP variation the clinical prognosis examined．Resul缸20 of ARDS patients died。10 survived．There significant difference(P0．05)between the death group and survival group in CRP baseline value(when diagnosed)．The CRP values after treatment a弛 lower than before treatment in survival group．whereas in the death group．3 ca8鹅decreased after treatment and 17 increased．There significant difference in CRP level after treatment and when compared 访tll CRP level before treatment and after treatment between the groups(P0．01)．’11Ie morality of patients with decreased CRP level after treatment(23．1％，3／13)was significantly lower than the pafients with elevated CRP level(100％．17／17)(P0．01)．Conclusions I)ynalmc observation of CRP will help to predict the clinical prognosis and direct the treatment． Key words ARDS； CRP：Prognose 急性呼吸窘迫综合征(ARDS)病因及发病机制