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choice question
Immunological unresponsiveness to self antigens is called: A
Tolerance B. Tolerogen C. Memory D. Acquired immunity
The signal transduction molecules associated with BCR are: B
CD21 and CD81 B. Igɑ and Igβ(CD79a and b). C. IgD and IgM D. ITAMs and ITIMs
T cells are MHC-restricted in their ability to respond to antigen because: D
All antigen must be processed and presented to activate lymphocytes
During an infection, all cells in the body present antigen on MHC Class I
MHC binds antigen more specifically than TCR does.
TCR must recognize both antigen and MHC molecules.
Positive selection in the thymus is mediated by:A
Thymic epithelial cells B. Macrophages C. Dendritic cells D B-cells
CD8 is a marker of :C
B cells B. Helper-T cells C. cytotoxic T cell D. Mφ
MHC class II molecules are found on: B
Virtually all cells in the body B. B cells, DC and Mφ
C Virtually all nucleated cells in the body D. Only on virally-infected cells
Which of the following is NOT ture of CD4+ and CD8+ cell markers? D
These are both surface glycoproteins expressed on T-cells
These serve to distinguish different types of T-cells, e.g., helper, suppressor and cytotoxic, from each other.
These are not found associated with immuogobulins
Both of the markers are present on all T-cells
Dendritic cells are characterized by: D
The presence of major basic protein B. expression of CD3 C. expression of IgM molecules
D their interface between the innate and adaptive immune system
Opsonization of bacteria occurs through coating bacteria just with:A
C3b B. C8 C. Membrane attack complex D. IgM
The following is characteristic of B cells but not T cells: D
Class I MHC B. CD3 C. HIV virus receptor D. Surface immunoglobulin
The thymus is the site of initial differentiation for: D
B cells B. Erythrocytes C. Hematopietic stem cells D. T cells
The membrane attack complex consists of :C
OH B. C3b2a, Bb C. C5b6789 D. Properdin
T-cells CD40L provides a cost
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