组合型人工肾技术预防血液透析中低血压的效果观察.docxVIP

组合型人工肾技术预防血液透析中低血压的效果观察 Abstract：Objective To observe the value of combined artificial kidney technique with hemodialysis combined with hemoperfusion in the treatment of uremia dialysis to prevent hypotension.Methods From January 2015 to January 2016，42 patients with nephropathy who needed hemodialysis were selected and divided into study group and reference group，21 cases each.The patients in the study group were treated with combined artificial kidney technique，and the patients in the control group were treated with routine hemodialysis.Observed the treatment effect of two groups of patients.Results The combined artificial kidney technique used in the study group made the molecular substance parathyroid hormone significantly higher than that of the control group，the difference was statistically significant（P0.05）.The study group 2～3 h blood pressure dialysis was better than the reference group，the difference was statistically significant（P0.05）.Conclusion The combined artificial kidney technique has significant effect in clinical treatment， which can effectively prevent the occurrence of hypotension during hemodialysis and reduce the risk of treatment，which is worthy of clinical application. Key words：Hypotension；Hemodialysis；Combined artificial kidney technology 血液透析（hemodialysis，HD）是急慢性腎功能衰竭患者肾脏替代治疗方式之一。在血液透析治疗中很容易引发其他不良病症，其中低血压的出现概率极高，在透析时患者的收缩压下降20～100 mmHg，带有或不带有低血压的症状，会导致心律不齐及组织血液流通不畅，长期低血压加快晚期肾衰竭患者残存肾单位减少，如果得不到及时有效的治疗，就会出现昏迷甚至死亡等危险情况[1-2]。本次研究给予透析中时常出现低血压的患者实施组合型人工肾技术，取得了较好的临床疗效，现报告如下。 1 资料与方法 1.1一般资料 选取2021年1月～2021年1月我院收治的尿毒症患者42例，研究经过本院医学伦理委员批准。纳入标准：所有患者均符合血液透析的诊断标准且入院时意识清晰，并自愿参与本次调查研究。排除标准：严重器质性疾病及药物过敏患者。其中男26例，女16例，年龄45～85岁，平均年龄（65±5.5）岁。患者病种归类：19例高血压肾病，12例原发性肾小球肾炎，5例糖尿病肾病，3例系统性红斑狼疮肾病，3例多囊肾病。需要血液透析的时间为8～120个月，2～3次/周，所有患者在维持性血液透析中易出现低血压的情况。 1.2方法 1.2.1透析方法 针对参照组患者实施常规得血液透析：应用瑞典金宝血液透析机，费森尤斯透析器，有效膜面积0.8～2.2 m2，采用碳酸氢盐透析液（规格：250 ml∶12.5 g/瓶，湖南康源制药有限公司，国药准字H***-*****），流量500 ml/min，电导度为140 ms/cm，血流量为200～250 ml/min，透析液温度为37 ℃，超滤率0.5～