会议ppt 201410脑网络文献学习contributions and challenges for network models in cognitive neuroscience.pptVIP

Contributions and challenges for network models in cognitive neuroscience Nature neuroscience 2014 陈曦 The article surveys applications of networks in descriptive accounts of brain organization, their utility for clarifying the relation of localized and distributed aspects of cognitive function their growing role as a basis for computational models of brain activity. *  Network models describe brain organization graph theory network models represent complex systems as sets of discrete elements (nodes) and their mutual relationships (edges) that can be summarized in the form of a connection matrix. The relations of nodes and edges define the network’s topology, amenable to descriptive analysis through a broad array of measures that probe local and global aspects of network organization  Brain networks fall into two different categories: Structural networks represent anatomical wiring diagrams, while functional networks are derived from estimates of interactions among time series of neuronal activity Node definition: Node definition is relatively unambiguous at the neuronal scale. However, at the large scale of whole-brain data sets, node definition requires partitioning or parcellation of the brain into regions or areas that are internally coherent according to anatomical or functional criteria parcellation—remain challenging in cerebral cortex. random partitioning of gray-matter voxels into equal-sized clusters strategies that use cytoarchitectonics or anatomical landmarks. Particularly promising are data-driven approaches based on the detection of boundaries in structural or functional connectivity profiles, region-growing and clustering methods, or a combination of connectivity and activation-based partitioning criteria. edges definition: In structural networks-- binary adjacency matrices; labeling density ; in the case of diffusion imaging, density of tractography streamlines, connection probabilities or indices of myelination status to es