支气管肺泡灌洗液13βD葡聚糖检测对侵袭性肺部真菌感染的（基础医学范文）.docVIP

支气管肺泡灌洗液13βD葡聚糖检测对侵袭性肺部真菌感染的（基础医学范文） 文档信息 属性： F-00PA94，doc格式，正文7426字。质优实惠，欢迎下载！ 适用： 作为文章写作的参考文献，解决如何写好实用应用文、正确编写文案格式、内容摘取等相关工作。 作者： 佚名 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 搞要 1 关键字：支气管肺泡灌洗液； （1，3）-β-D葡聚糖； 侵袭性肺部真菌感染； 诊断阈值 2 2 结果 5 3 讨论 5 参考文献 7 论文原创声明（模板） 10 论文致谢（模板） 10 正文 支气管肺泡灌洗液13βD葡聚糖检测对侵袭性肺部真菌感染的（基础医学范文） 搞要 摘要：目的：评价支气管肺泡灌洗液（BALF）中（1，3）-β-D葡聚糖（BG）含量的检测（G试验）对侵袭性肺部真菌感染（IPFI）的诊断价值，并寻找最佳诊断阈值。方法：选取2015年7月-2017年3月本院经病理组织学诊断或临床诊断的IPFI患者30例作为试验组，另选取同期本院单纯肺炎患者30例为对照组。两组患者均行支气管镜肺泡灌洗术，同时检测患者BALF和血液的BG的含量，评价其诊断效能，并绘制ROC曲线。结果：两组患者BALF和血液G试验的BG水平比较，差异均有统计学意义（）。BALF的G试验灵敏度90%、特异度%、准确度%、Youden指数、阳性预测值%、最佳诊断阈值为ng/L；血液的G试验灵敏度%、特异度%、准确度%、Youden指数、阳性预测值%、最佳诊断阈值20ng/L。结论：BALF的G试验较血液的G试验对IPIF诊断可能更有临床价值 关键字：支气管肺泡灌洗液； （1，3）-β-D葡聚糖； 侵袭性肺部真菌感染； 诊断阈值 【Abstract】 Objective：To evaluate the diagnostic value of bronchoalveolar lavage fluid（BALF）（1，3）-β-D glucan（BG） content（G test） in invasive pulmonary fungal infection（IPFI），and to find the best diagnostic ：30 patients with IPFI diagnosed by histopathology or clinical diagnosis in our hospital from July 2015 to March 2017 were selected as experimental group，30 patients with simple pneumonia in the same period were selected as control were treated with bronchoalveolar lavage，the BG content of BALF and blood were detected，the diagnostic efficacy of BALF and blood were evaluated，and the ROC curve was ：The BG levels of BALF and blood G test in two groups were compared，the differences were statistically significant（）.The sensitivity of BALF for G test was 90%，specificity was %，accuracy was %，Youden index was ，positive predictive value was %，and the optimal diagnostic threshold was ng/ sensitivity of blood G test was %，specificity was %，accuracy was %，Youden index was ，positive predictive value was %，and the best diagnostic threshold was 20 ng/：The G test of BALF may be more valuable for IPFI diagnosis than G test of blood. 【Key words】 bronchoalveolar lavage fluid； （1，3）-β-D glucan； Invasive pulmonary fungal infection； Diagn