细胞生物学：第十一章 细胞外基质及其与细胞的相互作用.pptVIP

* * Fibrillin原纤维蛋白 * 具有纤粘连蛋白的玻璃条对来自鸡胚神经系统的一群称为神经脊细胞具有迁移能力的细胞具有吸引力,细胞从别处爬行聚集并在此停止迁移 * * * Modes of action of the matrix metalloproteinases. (A) MMPs may affect cell migration by changing the cells from an adhesive to non adhesive phenotype and by degrading the ECM. (B) MMPs may alter ECM microenvironment leading to cell proliferation, apoptosis, or morphogenesis. (C) MMPs may modulate the activity of biologically active molecules such as growth factors or growth factor receptors by cleaving them or releasing them from the ECM. (D) MMPs may alter the balance of protease activity by cleaving the