成人软组织肉瘤化疗.pptxVIP

成人软组织肉瘤化疗Contents OverviewDrugsTreatmentneoadjuvant chemotherapyadjuvant chemotherapyAdvanced or metastatic diseases chmeotherapytargeted therapyContents OverviewDrugsTreatmentneoadjuvant chemotherapyadjuvant chemotherapytargeted therapySarcomas constitute a heterogeneous group of rare solid tumors ofmesenchymal cell origin with distinct clinical and pathological features成人软组织肉瘤（Soft tissue sarcomas ，STSs），包括一组发病相对较少，组织学多样的恶性肿瘤。起源中胚层和外胚层。占成人恶性肿瘤的1%和儿童恶性肿瘤的5%。尚无特别有效的治疗方法，需多学科联合。 Categories Sarcomas of soft tissues (including fat, muscle, nerve and nerve sheath, blood vessels, and other connective tissues) Sarcomas of bone.The anatomic site of the primary diseaseExtremities (60%) the trunk (19%) retroperitoneum (15%) head and neck (9%)Risk factorsAge. Soft tissue sarcomas can occur at any age, but overall are more common in older adults. The average age at diagnosis is 57 years. Certain types of sarcomas are more common in children, however. Chemical exposure. Being exposed to certain chemicals, such as vinyl chloride and dioxin, can increase the risk of soft tissue sarcomas. Radiation exposure. Previous radiation treatment for other cancers can increase the risk of soft tissue sarcomas.Signs and symptomsa new lump or a lump that is growing anywhere in the body may or may not cause pain may include abdominal swelling or a lump in the abdomennausea vomiting heartburn abdominal pain blood in vomit or stoolAdult soft tissue sarcoma diagnosed/Common/PopUps/popDefinition.aspx?id=46698version=Patientlanguage=EnglishIncisional biopsy: The removal of part of a lump or a sample of tissue. /Common/PopUps/popDefinition.aspx?id=45657version=Patientlanguage=EnglishCore biopsy: The removal of tissue using a wide needle. /Common/PopUps/popDefinition.aspx?id=46411version=Patientlanguage=EnglishExcisional biopsy: The removal of an entire lump or area of tissue that doesn’t look normal.core needle biopsyPathology and stagingthe type of soft tissue sarcoma the stage of the cancer (how f