角膜前基质针刺术治疗大泡性角膜病变的初步疗效观察.docVIP

角膜前基质针刺术治疗大泡性角膜病变的初步疗效观察 杨于力，张辰星，郑 莎，李灿，谢汉平 补充单位 补充单位 作者单位：第三军医大学 西南医院 西南眼科医院 重庆 400038 通讯作者：谢汉平, E-mail: xiehanping@ 第一作者：杨于力，女，博士学历，主治医师。E-mail:yangyuli1979@ 电话目的 观察及评价角膜前基质针刺术治疗大泡性角膜病变的疗效。方法 2008年5月至今在我院就诊的共11例11眼大泡性角膜病变（bullous keratopathy，BK）患者根据纳入及排除标准纳入实验研究，采用角膜前基质针刺术（anterior stromal micropuncture, ASP）治疗。采用30G的针头行角膜基质层针刺约200点，周边角膜部不进行穿刺。所有11例患者术后按照1、4、12、24周随访复查。观察和评价内容为患者术前及术后的眼部刺激症状（眼痛、眼部异物感、畏光），裂隙灯显微镜检查角膜水肿、上皮水泡，角膜荧光素染色检查角膜上皮有无缺损。结果结果应具体，并补充P值 11例患者术前与术后1，4，12，24周各时间点的角膜疼痛、畏光、流泪程度比较结果提示差异有统计学意义(P0.05)，表明患者在行ASP治疗后明显降低了术前眼部的刺激症状。裂隙灯显微镜检查角膜情况，角膜水肿均明显缓解，上皮水泡消失，角膜荧光素染色角膜上皮完整。结论 角膜前基质针刺术是一种操作简单、有效、经济的手术方式，对于视功能恢复潜力差，患者无条件接受角膜移植手术的大泡性角膜病变患者（如单纯为解除眼部症状）可首选角膜前基质针刺术。 结果应具体，并补充P值 [关键词] 大泡性角膜病变；角膜前基质针刺术补充关键词；角膜水肿；疼痛；畏光；异物感 补充关键词 [中图法分类号] [文献标志码] A Anterior stromal puncture in bullous keratopathy A clinicopathologic study 补充英文题目和作者拼音以及单位。 Yang Yuli, Zhang chenxing, Zhen sha ,Li can , Xie Hanping 补充英文题目和作者拼音以及单位。 Southwest Hospital, Southwest Eye Hospital, Third Military Medical University, Chongqing, 400038 Objective This study was designed to evaluate the effect of anterior stromal puncture to treat patients with symptomatic bullous keratopathy (BK). Methods We reviewed the medical records of 11 patients 11 eyes who were diagnosed as BK in Southwest eye hospital since 2008 May. Anterior stromal micropuncture (ASP) were performed fot the patients. Approximately 200 punctures were given with a bent 30-gause needle sparing the peripheral cornea.中文摘要中请加入这句话。 All the patients were questioned about pain intensity, foreign-body sensation, and photophobia before and 1,4,12 and 24 weeks after the treatment. Slit-lamp biomicroscopy results were also evaluated. The results before and after the treatment were compared with software SPSS 13.0. Results The comparisons among before and 1, 4, 12, 24 weeks after the ASP of pain (P0.05),photophobia(P0.05), foreign-body sensation(P0.05) showed statistical d