COPD患者联合使用噻托溴铵和沙美特罗丙酸氟替卡松的疗效评估临床医学.docVIP

COPD患者联合使用噻托溴铵和沙美特罗丙酸氟替卡松的疗效评估临床医学 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：COPD患者联合使用噻托溴铵和沙美特罗丙酸氟替卡松的疗效评估临床医学 1 1 资料与方法 3 2 结果 4 3 讨论 5 文2：噻托溴铵和沙美特罗丙酸氟替卡松治疗老年COPD研究临床医学 8 1 资料与方法 8 2 结 果 9 3 讨 论 10 参考文摘引言： 11 原创性声明（模板） 13 文章致谢（模板） 13 正文 COPD患者联合使用噻托溴铵和沙美特罗丙酸氟替卡松的疗效评估临床医学 文1：COPD患者联合使用噻托溴铵和沙美特罗丙酸氟替卡松的疗效评估临床医学 【Abstract】 Objective To explore the effects of combining tiotropium bromide and salmeterol/fluticasone propionate on patients with COPD by analysing lung function and arterial blood gas relevant 42 patients with COPD were randomly divided into two groups:experimental group（20 cases） and control group（22 cases）.The basic regime for the two groups were oxygen inhalation, antibiotics ,aminophylline , stopping coughing and eliminating sputum. The experimental group was given tiotropium bromide and salmeterol/fluticasone control group was given tiotropium bromide. After leaving hospital , the experimental group continued using tiotropium bromide and salmeterol/fluticasone propionate;the control group continued using tiotropium bromide during 6 patients underwent pulmonary function test and arterial blood gas analysis before treatment,7 days and 6 weeks after Before treatment ,lung function and arterial blood gas relevant paramete in both groups are not statistically different （P）.After therapy, there was improvement of lung function and arterial blood gas relevant paramete in both groups than befroe treatment（P）. FVC，FEV1 ,FEV1%Pred, PaO2 and PaCO2 were superior in experimental group to control Compared with using tiotropium bromide alone, combining tiotropium and salmeterol/fluticasone propionate can improve lung function and arterial blood gas more significantly. 【Key words】 chronic obstructive pulmonary disease（COPD）; pulmonary function test;blood gas analysis ; tiotropium bromide; salmeterol/fluticasone propionate 慢性阻塞性肺疾病（chronic obstructive pulmonary disease, COPD）是一种发病率和死亡率非常高的慢性疾病。它以气流受限为特征，在临床上以咳嗽、咳痰、呼吸困难为主要表现。近年来对COPD的