诊治进展english多囊卵巢综合症.pptVIP

多囊卵巢综合症诊治进展Polycystic Ovary Syndrome (PCOS)----Progress in Diagnosis and Therapy 浙江大学医学院附属妇产科医院 Women’s Hospital, School of Medicine, ZJU 朱小明 Xiaoming Zhu (ntzhuxm@) Outline Definition of PCOS Pathogenesis of PCOS Diagnosis criteria of PCOS Differentiation in diagnosis of PCOS Therapy of PCOS Definition of PCOS-1 A syndrome of ovarian dysfunction Along with the cardinal features hyperandrogenism (HA) polycystic ovary (PCO) morphology. Its clinical manifestations include: menstrual irregularities, signs of androgen excess and obesity. IR and elevated serum LH levels are also common features. Associated with an increased risk of type 2 diabetes and cardiovascular events. The 2003 Rotterdam consensus workshop Definition of PCOS-2 A hyperandrogenic disorder PCO should be considered, although not all; Ovulatory dysfunction is a prominent, but not a universal feature. Other well-defined disorders had to be excluded. JCEM 2006, The Androgen Excess Society (AES) Definition of PCOS-3 The condition that have a major effect throughout life on the reproductive, metabolic, and cardiovascular health. Simplified by Ehrmann DA in N Engl J Med 2005;352:1223 Pathophysiologic Features of PCOS-1 A syndrome of ovarian dysfunction Along with the cardinal features hyperandrogenism （HA） polycystic ovary (PCO) morphology. Its clinical manifestations include: menstrual irregularities, signs of androgen excess and obesity. IR and elevated serum LH levels are also common features. Associated with an increased risk of type 2 diabetes and cardiovascular events. The 2003 Rotterdam consensus workshop Pathophysiologic Features of PCOS-2 The condition that have a major effect throughout life on the reproductive, metabolic, and cardiovascular health. Simplified by Ehrmann DA in N Engl J Med 2005;352:1223 Outline Definition of PCOS Pathogenesis of PCOS Diagnosis criteria of PCOS Differential diagnosis of PCOS Therapy of PCOS Pathogenesis of PCOS —overview Not clear Genetic backgr