染色体结构变异(SV)与NGSPPT课件.ppt

染色体结构变异（ SV ）与NGS;目录;目录;SV的概念;SV的概念;目录;SV的分类;SV的分类;目录;SV的形成机制;目录;SV的影响;目录;染色体显带技术(chromosome banding);荧光原位杂交(Fluorescence?in situ?hybridization); 微阵列比较基因组杂交(array comparative genomic hybridization ,aCGH) ;SNP芯片(SNP array);SV的NGS检测原理;NGS检测程序;CNV检测;目录;融合基因的定义;基因融合机制;Breast cancer associated read-through fusion transcripts;cis-splicing;The generation of chimeric gene products by trans-splicing of RNA and by gene fusion;目录;RNA is better for fusion detection than hybrid capture;STAR-Fusion;Ion AmpliSeq? RNA Fusion Lung Cancer Research Panel;Ion AmpliSeq? RNA Fusion Lung Cancer Research Panel;Ion Am