关于孤束核在针刺足三里调节胃运动中的作用机制.docVIP

关于孤束核在针刺足三里调节胃运动中的作用机制 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：关于孤束核在针刺足三里调节胃运动中的作用机制 1 1 材料与方法 3 2 结果 7 3 讨论 7 文2：针刺内关足三里等穴对大鼠孤束核神经元放电的影响 8 参考文摘引言： 15 原创性声明（模板） 16 文章致谢（模板） 17 正文 关于孤束核在针刺足三里调节胃运动中的作用机制 文1：关于孤束核在针刺足三里调节胃运动中的作用机制 Abstract：Objective To research the function of the vagus nerve center nucleus of solitary tract (NTS) in the influence of gastric pressure by acupuncture at “Zusanli” in rats with motility disturbances of the stomach. Methods Adopting electrophysiological methods， the extracellular discharge signals of neuronic action in NTS were recorded with glass microelectrode. The influence of the discharges of NTS neuro and gastric pressure responding to the acupuncture at “Zusanli” point were observed in normal status and the condition of Atropine or Metoclopramide intravenous injection. Results In the normal status， acupuncture at “Zusanli” activated the discharges of NTS neuro and promote the gastric pressure remarkably. After Atropine intravenous injection， the background discharges of NTS neuro decreased. There was no statistical difference in the discharges responding to the effect of acupuncture before and after Atropine administration. And the gastric motion reinforced obviously by acupuncture at “Zusanli” after Atropine administration. But after intravenous injection of Metoclopramide， the background discharges of NTS neuro increased. There was also no statistical difference in the discharges responding to the effect of acupuncture before and after Metoclopramide administration. Moreover， the function of promoting gastric motion by acupuncture at “Zusanli” got more obviously after Metoclopramide administration. Conclusion The function of adjusting gastric motion by acupuncture at “Zusanli” point has close relation to the activation of NTS neuro， and the increasing amplitude of the discharges of NTS neuro wasn’t influenced by cholinergic receptor blocker Atropine and dopamine-receptor antagonist Metoclopramide。 Key w