浅论流行性乙型脑炎患儿白介素1β神经元特异性烯醇酶的变化及临床意义（临床医学论文资料）.doc

浅论流行性乙型脑炎患儿白介素1β神经元特异性烯醇酶的变化及临床意义（临床医学论文资料） 文档信息 ： 文档作为关于“医学心理学”中“儿科学”的参考范文，为解决如何写好实用应用文、正确编写文案格式、内容素材摘取等相关工作提供支持。正文8642字，doc格式，可编辑。质优实惠，欢迎下载！ 目录 TOC \o "1-9" \h \z \u 目录 1 正文 1 文1：浅论流行性乙型脑炎患儿白介素1β神经元特异性烯醇酶的变化及临床意义 2 1材料和方法 3 文2：流行性乙型脑炎患儿白介素1β神经元特异性烯醇酶的变化及意义临床医学论文 6 1??材料和方法 7 2??结果 8 3??讨论 9 参考文摘引言： 11 原创性声明（模板） 12 文章致谢（模板） 13 正文 浅论流行性乙型脑炎患儿白介素1β神经元特异性烯醇酶的变化及临床意义（临床医学论文资料） 文1：浅论流行性乙型脑炎患儿白介素1β神经元特异性烯醇酶的变化及临床意义 Abstract: ? Objective: To study the changes of interleukin-1β(IL-1β) and neuron-specific enolase (E) both in cerebrospinal fluid (CSF) and serum in children with Japanese encephalitis and the clinical significance of the changes. Methods:?Fifty cases of children with Japanese encepha-litis were observed，which were divided into three groups according to Glasgow score:?normal group (17 cases)， general group?(20 cases)?and severe group?(13 cases). IL-1β and E were detected both in CSF and serum in the very and recovery period in 50 cases， and at the same time 20 cases of children without central nervous system disease were selected as control. IL-1β was determined with enzyme-linked immunosorbent assay?(ELISA)，E was determined with electrochemiluminescence. Results:?The levels of IL-1β and E in CSF and serum in children with Japanese encephalitis in very and recovery period were both significantly higher than those of the control (P?)， and the degree was parallel to the severity of the disease (P?). The levels of IL-1β?in CSF and serum were positively correlated (P?)，so were the levels of E in CSF and serum?(P?).?Simultaneously，the levels of IL-1β and E in CSF were positively correlated (P?)，?so were the levels in serum (P?). Conclusion:?To detect the IL-1β and E in CSF and serum is helpful for our judgement of the degree of children’brain injured and assessment of clinical condition of children with Japanese encephalitis。 Key words: ? interleukin-1β;neuron-specific enolase;Japanese encephalitis;cerebrospinal fluid;serum 白介素1β(IL-1