替格瑞洛与氯吡格雷治疗冠心病心肌缺血的临床效果对比.docxVIP

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替格瑞洛与氯吡格雷治疗冠心病心肌缺血的临床效果对比.docx

替格瑞洛与氯吡格雷治疗冠心病心肌缺血的临床效果对比 【摘要】目的:对比研究冠心病心肌缺血治疗中替格瑞洛与氯吡格雷的临床疗效。方法:此次68例研究对象均为笔者所在医院2018年1月-2019年2月收治的冠心病心肌缺血患者,按照双模拟法1∶1分成研究组和参照组,各34例。研究组应用替格瑞洛,参照组应用氯吡格雷,对比两组应用效果。结果:研究组治疗总有效率为91.18%,高于参照组的70.59%,差异有统计学意义(p0.05)。治疗后研究组心率、胆固醇、甘油三酯、血液黏稠度均低于参照组,差异均有统计学意义(p0.05)。研究组不良反应发生率为5.88%,低于参照组的23.53%,差异有统计学意义(p0.05)。结论:在冠心病心肌缺血治疗中替格瑞洛比氯吡格雷效果显著,能更快改善病症、促进病情恢复,且不良反应率低,更值得在临床中推广应用。 【关键词】替格瑞洛;氯吡格雷;冠心病;心肌缺血 doi:10.14033/j.cnki.cfmr.2019.27.067文献标识码b文章编号1674-6805(2019)27-0-03 comparativeanalysisofclinicalefficacyofticagrelorandclopidogrelintreatmentofmyocardialischemiainpatientswithcoronaryheartdisease/zhaofang.//chineseandforeignmedicalresearch,2019,17(27):-158 【abstract】objective:tocomparetheclinicalefficacyofticagrelorandclopidogrelintreatmentofcoronaryheartdiseasewithmyocardialischemia.method:atotalof68subjectswereallcasesofcoronaryheartdiseasewithmyocardialischemiafromjanuary2018tofebruary2019inourhospital.accordingtothedoublesimulationmethod,theyweredividedintostudygroupandreferencegroup,34casesineachgroup.thestudygroupwastreatedwithticagrelor,andthereferencegroupwastreatedwithclopidogrel,thetheapplicationeffectofthetwogroupswerecompared.result:thetotaleffectiverateofthestudygroupwas91.18%,whichwashigherthan70.59%ofthereferencegroup(p0.05).aftertreatment,theheartrate,cholesterol,triglyceride,andbloodviscosityofthestudygroupwerelowerthanthoseofthereferencegroup(p0.05).theincidenceofadversereactionswas5.88%inthestudygroup,whichwasmuchlowerthan23.35%inthereferencegroup(p0.05).conclusion:inthetreatmentofmyocardialischemiaofcoronaryheartdisease,tigrilolhasamoresignificanteffectthanclopidogrel,andcanimprovethediseasefasterandpromotetherecoveryofthedisease,withalowrateofadversereactions.therefore,itisworthpromotingtheapplicationinclinicalpractice. 【keywords】tigrelor;clopidogrel;coronaryheartdisease;myocardialischemia first-author’saddress:xuan’encountypeople’shospital,xuan’en445500,china 冠心病患者常伴隨心肌缺血,这是因为患者心脏血液灌注量减少后,降低了心肌正常代谢功能,导致心脏不能正常工作,属于一种的病理状态,在临床中

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