医学meta分析数据提取表格1.docxVIP

Study Year Ethnicity Age(year) Male(％) BMI(kg/m2) Current smoker(%) Lonn et al. Cole et al. 2006 Mixed 2007 Mixed 68.9 57 71.8 63.8 29.7 27.5 11.5 14.5 Logan et al. Zhang et al. Wu et al. Armitage et al. Hankey et al. Gao et al. 2008 Caucasian 2008 Caucasian 2009 Caucasian 2010 Caucasian 2012 Mixed NR NR 0 NR 30.6 25.7 NR NR 11.9 7 62.8 65.3 64.2 NR 38.4 83 12 63.9 50.3 NR 23.3 17.3 2013 Asian 60.5 NR Folic （mg） Durations(months) active control 2.5 60 75 50 3 37 4 1 0.5 2.5 1 27 88 57 80 41 36 10 18 1 10 22 3 2 86 21 2 91 21 2 2.5 1 Prior diseases(daily) Vascular disease or diabetes Colorectal adenoma Colorectal adenoma CVD or 3 or more coronary risk factors Colorectal adenoma MI, other CHD, other vascular disease or diabetes Stroke or transient ischemic attack None Additional treatment 50 mg vitamin B6 and 1 mg vitamin B12 81 mg or 325 mg aspirin or none 300 mg aspirin or none 50 mg vitamin B6 and 1 mg vitamin B12 None 1 mg vitamin B12 50 mg vitamin B6 and 1 mg vitamin B12 None