放射治疗联合微波热疗治疗晚期颈部淋巴结转移癌60例.docVIP

放射治疗联合微波热疗治疗晚期颈部淋巴结转移癌60例 放射治疗联合微波热疗治疗晚期颈部淋巴 结转移癌60例 医学信息内?外科版2009年7月第22卷第7期 放射治疗联合微波热疗治疗晚期 颈部淋巴结转移癌60例 ? 601? 靳彩玲,刘晶,牛红蕊,王巧枝,苗战会 (新乡医学院第一附属医院肿瘤科,河南卫辉453100) 摘要:目的探讨放射治疗与微波热疗联合治疗晚期颈部淋巴结转移癌的临床疗效.方法对60例颈部 淋巴结转移癌患者行单纯放疗和放疗加微波热疗,单纯放疗组:采用直线加速器6MV—X治疗,累计肿瘤剂量 60,70Gy/6,7周;放疗加微波热疗组:放疗同单纯放疗组,微波热疗采用HG一2000型微波治疗机对颈部淋 巴结转移灶区域局部体外加热.3O,40min/次,2次/周,治疗结束后3月进行疗效评价.结果单纯放疗组 CR30.0%,放疗加微波组CR56.7%,两者之间比较有显着性差异(Plt;0.05);总有效率(CR+PR)单纯放疗 组63.3%,放疗加热疗组CR+PR90.0%,两者之间有显着性差异(Plt;0.05).结论微波热疗对放疗有协同 增敏作用,二者配合对颈部较淋巴结转移癌的治疗有重要的临床应用价值. 关键词:颈部淋巴结转移癌;放射治疗;微波治疗 中图分类号:R73文献标志码:A文章编号:1006—1959(2009)07—0601—02 Clinicalobservationofmetastaticcarcinomaofcervicalnodebyradiationtherapyandmicrowavetherap y JINCai—ling,LIUJing,NIUHong—rui,etal (DepartmentofOncology,theFirstAffiliatedHospitalofXinxiangMedicalUniversity,Weihui453100, HenanProv- ince,China) Abstract:ObjectiveToexploretheclinicalefficacyofmetastaticcarcinomaofcervicalnodewithradiati ontherapy andmicrowavetherapy.MethodsSixtypatientswithmetastaticcervicalnodeweretreatedwithradiation therapyalone andradiationtherapywithmicrowavetherapy.Radiationtherapygroupalone:lineraccelerator6MV—Xwasusedto give60—70Gyin6to7weeks;Radiationtherapyandmicrowavetherapygroup:HG一2000microwavemachinewas usedtotreatmetastaticcervicalnodefor2timesinoneweek,30or40minutespertime.Theclinicalefficac ywase? valuated3monthslater.ResultsCompleteresponserateswere30.0%and56.7%inradiationtherapygrou palone andradiationtherapywithmicrowavetherapygroup,respectively.Therewasobviousdifferenceinresp onsebetween thetwogroups(Plt;0.05);thetotaleffectiveratewere63.3%and90.O%intwogroups,includingcompl eterespon— sesandpartialresponses.Therewasobviousdifferenceinresponsebetweenthetwogroups(Plt;0.05). Conclusions Thecombinationoftwomethodsiseffectiveandsignificantlysuperiortosingletreatmentofradiotherap y. Keywords:cervicallymphnodemetastaticcarcinoma;radiation;microwavetherapy 肿瘤热疗学是一门利用热的生物效应治疗肿瘤的 学科,近20年来由于多学科的介入,热疗仪器的不断 推陈出新,使肿瘤热疗获得迅速发展,已成为继手术, 放射治疗,化