细胞膜的结构及探索历程.pptxVIP

会计学第1页/共52页第2页/共52页细胞质膜在维持胞内环境的相对稳定，细胞与环境之间的物质运输、能量转换及信息传递过程中有重要作用。细胞内膜系统和细胞质膜统称为生物膜。第一节 细胞质膜的结构模型第3页/共52页一、生物膜的结构模型：1 质膜结构研究历史的回顾：第4页/共52页Overton(1890s): Lipid nature of PM;? J.D.Robertson(1959): The TEM showing:the trilaminar appearance of PM; Unit membrane model;? S.J.Singer and G.Nicolson(1972): fluid-mosaic model;? K.Simons et al(1997): lipid rafts model; 第5页/共52页第6页/共52页 Singer and Nicolson’s Model of membrane structure: The fluid-mosaic model is the “central dogma” of membrane biology. The Fluid Mosaic Model, proposed in 1972 by Singer and Nicolson, had two key features, both imp