GLUT1-IN-2-DataSheet-生命科学试剂-MCE.pdf

Hotline: 400-820-3792 Inhibitors • Screening Libraries • Proteins www.MedChemE GLUT1-IN-2 Cat. No.: HY-148315 CAS No.: 305357-89-5 分⼦式: C₂₁H₁₇N₃O 分⼦量: 327.38 作⽤靶点: GLUT 作⽤通路: Membrane Transporter/Ion Channel 储存⽅式: Please store the product under the recommended conditions in the Certificate of Analysis. BIOLOGICAL ACTIVITY ⽣物活性 GLUT1-IN-2 (compound 17) 是 GLUT1 抑制剂，IC50 值为 12 μM。GLUT1-IN-2 对恶性疟原⾍⼰糖转运蛋⽩ ( PfHT) 具有抑制效应，IC50 值为 13 μM。GLUT1-IN-2 可⽤于感染的研究。 IC50 Target IC50: 12 μM (GLUT1), 13 μM (PfHT) [1] 体外研究 GLUT1-IN-2 (0-100 μM) inhibits activities of GLUT1 and PfHT with IC50 values of 12 and 13 μM, respectively [1]. REFERENCES [1]. Ortiz D, et al. Identification of Selective Inhibitors of the Plasmodium falciparum Hexose Transporter PfHT by Screening Focused Libraries of Anti-Malarial Compounds. PLoS One. 2015 Apr 20;10(4):e0123598. McePdfHeight Caution: Product has not been fully validated for medical applications. For research use only. Tel: 400-820-3792; 021 Fax: 021