7-李勇—江西—肿瘤精准医学与大数据.pptxVIP

肿瘤、精准医学与大数据南昌大学第一附属医院肿瘤科 李勇 博士 Cancer Treatment Prior Sequencing of the Human GenomeLargely focused on use of cytotoxic chemotherapyTreatment has many side effectsRarely curative when used in metastatic setting Non-responders to oncology therapeutics are highly prevalent and very costly The evolution of the classification of non-small cell lung cancer Glioblastoma and Gastric carcinomaClassical, mesenchymal proneural and neuralEGFR CDKN2A, NF1 TP53 MET NFkb, PDGFRA HIF1 RBIDH1 1p19q MGMT、、、、EBV MSI GS CIN Clonal expansion and phenotypic diversification with tumor progress Robotic Prostatectom