失眠治疗趋势.ppt

  1. 1、本文档共40页,可阅读全部内容。
  2. 2、原创力文档(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。
  3. 3、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载
  4. 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
查看更多
失眠治疗趋势 We’ve learnedhow to sleep…… We’ve learnedhow not to sleep insomniaInsomnia symptoms(%)Insomnia syndrome (%)Initial24.65.5Middle15.13.4Terminal14.83.3Non-restorative39.19.3Mixed50.612.0Sleepless in TaiwanLee, Yue-Joe 2001 30kg Why Sleepless? Why Sleepless?貓熊怎麼睡你知道嗎?馬總統專程CALL動物園長詢問 ?????????????????????/referurl/news/logo/ettoday//SIG=10pugg0rl/*/台北報導 身體疾病導致失眠? Physical Illness (10%)精神疾病導致失眠? Mental Illness (40-50%)使用藥物/物質導致失眠? Substance/Drug (10%)睡醒週期障礙導致失眠? Circadian Disturbance不寧腿症候群或週期性肢體抽動障礙? RLS/PLMD 睡眠呼吸中止症? Sleep Apnea原發性失眠? Primary Insomnia (20-25%)猝睡症? Narcolepsy次發性失眠其他原發性睡眠障礙20-25%Why Sleepless? Neurophysiologic Models of InsomniaCircadian SystemArousal SystemHomeostatic SystemSleepNeuroPhysiologic Systems Homeostatic Regulation of SleepNeurochemical basis of sleep homeostasisAdenosineGenetic control of homeostatic processesSleep duration response to sleep loss may be affected by mutations of the murine Clock gene. Homeostatic Regulation in InsomniaLowered homeostatic sleep driveReduced EEG slow wave activity (Merica Gaillard, 1992)Behavioral factorsIncreased resting in bedSleeping outside of the nocturnal sleep periodReduced daytime activitiesCoffee drinking Circadian Process of SleepThe endogenous pacemaker regulates the sleep-wake rhythm with about 24 hour per cycle.Human circadian period is slightly longer than 24 hours.The center of circadian system:Suprachiasmatic nucleus (SCN)Dorsomedial hypothalamus (DHM) Biological Clock Circadian Regulation in InsomniaExtreme circadian type or less flexible circadian system as a predisposing factor for circadian rhythm sleep disordersDecreased melatonin levels?Behavioral FactorsIrregular or changes of sleep-wake scheduleSleep-in during weekend to catch up lost sleep Chronobiological ModelsNormal process S C in sleep deprivationRiemann D, et al. Biological Psychiatry. 2001;57:67-103. Why Sleepless? Why Sleepless? Why Sleepless?Insomniac’s BrainOnly Sleep Then, to fall asleep. NIH STATE-OF-THE-S

文档评论(0)

173****6638 + 关注
实名认证
内容提供者

该用户很懒,什么也没介绍

1亿VIP精品文档

相关文档