从基因组学到蛋白质组学.pptxVIP

从基因组学到蛋白质组学第1页/共20页 The Human Genome is encoded by 23 chromosome pairsThese encode ~20,300 different genesc.2001第2页/共20页 DNA is composed of 4 chemical bases (nucleic acids)A, G, C, TDNA double helixThe “simple” chemistry of DNA has industrialised genomics第3页/共20页 1st genome:$70MNow: $50K and decreasing rapidly第4页/共20页 第5页/共20页 CaterpillarButterflyGenome vs. ProteomeGenomes are static, Proteomes are dynamicHeartLiver第6页/共20页 HemoglobinAntibodyEpidermal Growth Factor ReceptorProteins are molecular machines of many shapes and sizesRubisco第7页/共20页 Proteins are composed of up to 20 amino acids- Dif