钴缺乏症的学习课件.pptxVIP

钴缺乏症的学习课件;第六节、钴缺乏症Section 6 Cobalt Deficiency;一、定义 Definition;在临床上是以厌食、消瘦和贫血等为主征的慢性代谢病。 Characterized clinically by: Inappetence (厌食), Gradual loss of body weight, Anemia or anaemia(贫血), Effects on reproductive performance. 本病属世界性地方病之一,反刍动物容易发病. Worldwide where soils are deficient incobalt. ;土壤中钴含量:0.2-18mg/Kg(DM) The concentration of cobalt in the soil(0.2~18mg/KgDM) 长期放牧在钴缺乏土壤(钴含量在0.25 mg/kg以下)的牧草场地或持续性饲喂钴缺乏(0.04-0.07mg/kg干重)草类或稻草的牛群，多有发病。 Grazing on pastures in the soil (containing less than 0.25 mg/kg cobalt )with deficient cobalt for long period Persistently feed pastures or straw containing less than 0.07 and 0.04 mg/kg DM Result in clinical disease in sheep and cattle 凡阻碍奶牛瘤胃内发酵过程中合成维生素B12的因子或疾病，可导致钴缺乏。 Resulting in a deficiency of vitamin B12. ;三、流行病学 Epidemiology;四、发病机理 Pathogenesis 1.钴是反刍兽必需的微量无素，在体内储量有限； Cobalt is unique as an essential trace element in ruminant nutrition it is stored in the body in limited amounts only and not in all tissues 2.钴只有在反刍动物瘤胃中，才能发挥其生物学作用：钴是维生素B12的 组成成分； Its only known function is in the rumen to participate in the production of vitamin B12 (cyanocobalamin氰钴维生素) ;四、发病机理 Pathogenesis;五、临床症状 Signs;六、临床病理 Clinical pathology 血清总蛋白含量减少，红细胞数减少，属红细胞大小不匀症和小细胞低染性贫血。 　 Serum albumen ? Erythrocyte ? Anemia(贫血) 血浆、肝脏和瘤胃内容物中钴含量减少，血清碱性磷酸酶活性下降。 Cobalt concentration of plasm、liver and rumen?; Serum alkaline phosphatase levels ?; ;六、临床病理 Clinical pathology;七、诊断 Diagnostic confirmation 在低钴地区的牛群，凡出现厌食、营养性消瘦和可视粘膜淡染(贫血)等症状时，便可怀疑钴缺乏症。 　 In area with deficient in cobalt, Inappetence;(厌食) Loss of body weight; (营养性消瘦) Anaemia; (贫血) 口服氯化钴水溶液，若使顽固性厌食等症消失，可治疗性诊断。 After the oral administration of cobalt， Inappetence signs disappearence. ;谢谢观看！