Cryptophane A，E合成与表征及其甲烷敏感特性的开题报告.docxVIP

Cryptophane A，E合成与表征及其甲烷敏感特性的开题报告 Title: Synthesis, Characterization, and Methane Sensing Properties of Cryptophane A and E Introduction: Cryptophanes are cyclic compounds with a hydrophobic cavity that has the ability to trap small molecules, such as gases. Cryptophane A and E are two of the most studied cryptophanes due to their unique and complementary properties. Cryptophane A has a smaller cavity size and higher affinity for methane, while Cryptophane E has a larger cavity size and higher affinity for ethane. In this report, we aim to synthesize Cryptophane A and E and characterize their structures using NMR spectroscopy. Additionally, we will investigate the methane sensing properties of these cryptophanes using gas chromatography. Objectives: 1. Synthesize Cryptophane A and E using established methods. 2. Confirm the structure of the synthesized compounds using NMR spectroscopy. 3. Evaluate the methane sensing properties of Cryptophane A and E using gas chromatography. 4. Compare the sensing properties of Cryptophane A and E and determine their applicability as gas sensors. Methods: 1. Synthesis of Cryptophane A and E: The synthesis of Cryptophane A and E will be carried out using established methods involving the cyclization of diesters with a bridging unit. 2. NMR Spectroscopy: The structure of the synthesized compounds will be confirmed using NMR spectroscopy. The ^1H-NMR and ^13C-NMR spectra will be obtained and analyzed to determine the chemical shifts and coupling constants. 3. Methane Sensing Properties: The methane sensing properties of Cryptophane A and E will be evaluated using gas chromatography. The cryptophanes will be coated onto a solid support and exposed to varying concentrations of methane. The response of the sensor will be measured and analyzed to determine the sensitivity and selectivity of each cryptophane. 4. Data Analysis: The results of the experiments will be analyzed and compared to determine the relative sensing properties of Crypt