阿替普酶联合银杏叶提取物治疗老年急性缺血性脑卒中的临床效果.pdfVIP

临床医学1程2023年4月第30卷第4期 ·497. ·论著· (临床研究） 阿替普酶联合银杏叶提取物治疗老年急性缺血性脑卒中的 临床效果 赵静雅，高洋，周淑芳 (河南大学淮河医院神经内科，河南开封475000) 【摘要】目的探讨阿替普酶联合银杏叶提取物治疗老年急性缺血性脑卒中（AIS ）的效果。方法100例老年AIS患者随机 分为两组，对照组采用阿替普酶治疗，观察组采用阿替普酶联合银杏叶提取物治疗，比较两组的治疗效果、日常生活能力、神经 功能缺损及神经递质水平。结果观察组的总有效率为94.00%，高于对照组的80.00%（P0.05)。治疗后，观察组的ADL评分 高于对照组，NIHSS评分低于对照组，5-HT、DA水平均高于对照组，Glu水平低于对照组（P0.05）。结论阿替普酶联合银 杏叶提取物治疗老年AIS可改善患者的日常生活能力，减轻神经功能损伤，其机制可能与调节神经递质表达有关。 阿替普酶；银杏叶提取物；急性缺血性脑卒中 【关键词】 中图分类号：R2-031 文献标识码：A doi:10.3969/j.issn.1674-4659.2023.04.0497 Clinical Effect of Alteplase Combined with Ginkgo Biloba Extract in the Treatment of Elderly Acute Ischemic Stroke ZH China) AO Jingya, GAO Yang, ZH0U Shufang (Department of Neurology, Huaihe Hospital of He nan University, Kaifeng 475000, [Abstract] Objective To explore the clinical effect of alteplase combined with Ginkgo Biloba extract in the treatment of elderly acute ischemic stroke (AIS). Methods 100 elderly patients with AIS were randomly divided into two groups. The control group was treated with alteplase, and the observation group was treated with alteplase combined with Ginkgo Biloba extract. The therapeutic effect, daily living ability, neurological deficit and neurotransmitter levels were compared between the two groups. Results The total effective rate of the observation group was 94.00%, higher than 80.00% of the control group (P0.05). After treatment, the ADL score of the observation group was higher than that of the control group, the NIHSS score was lower than that of the