药理学英文版教学课件：Chapter 11 Local anaesthetics.pptVIP

Local Anesthetics Case 1 16 yrs male Diagnosed as appendicitis and prepared for operation. Anesthesiaed with intraspinally(脊髓腔) injecting 2% lidocaine 1/200000 adrenaline. Definition Local anesthetics (,局部麻醉药) are drugs that block both the generation（产生） and the conduction（传导） of the nerve impulse when applied locally to nerve tissue in appropriate concentrations. Local anesthetics produce the reversible loss of sensation（感觉） without the loss of consciousness. The first local anesthetic found was cocaine（可卡因） . Owing to its addiction（成瘾性）, its clinical use was limited.