应用stata软件做meta分析与思维导图实例.pdfVIP

Impact of oral care with versus without toothbrushing on the prevention of ventilator- associated p onia: a systematic review and meta- ysis of randomized controlled trials 1† 2† 3† 1 1* Wan Jie Gu , Yi Zhen Gong , Lei Pan , Yu Xia Ni and Jing Chen Liu Introduction remains unclear. Moreover, VAP has been associated Ventilator-associated p onia (VAP) is defined as with prolonged duration of mechanical ventilation, p onia that occurs in patients receiving mechanical longer ICU stays, and higher health-care costs [3-5]. ventilation and that arises more than 48 to 72 hours Given the clinical consequences attributable to VAP, pre- after endotracheal intubation [1]. VAP remains one of vention of VAP is of great importance and is a priority in the most common ial infections in the intensive ICU care. care unit (ICU) and affects 8% to 28% of patients receiv- The main important mechanism for the development ing mechanical ventilation [2]. Although many studies of VAP is aspiration of colonized oropharyngeal secre- have tried to assess the mortality attributable to VAP, it tions into the lower respiratory tract [6]. The oral is a potential reservoir for bacteria and provides a habitat * Correspondence: jingche .cn for microorganisms responsible for VAP, so strategies to † Contributed equally redu