第二讲真核生物的转录详解.pptVIP

转录因子 分子量（kD) 功能 TBP 30 与TATA盒结合 TFⅡ-B 33 介导RNA聚合酶Ⅱ与TFIID的结合 TFⅡ-F 30,74 解旋酶 TFⅡ-E 34,37 促进TFIIH的激酶活性 TFⅡ-H 62,89 解旋酶、激酶、DNA的修复 TFⅡ-A 12,19,35 稳定TFⅡ-D的结合 TFⅡ-I 120 促进TFⅡ-D的结合 总结：各转录因子的作用 本文档共48页；当前第30页；编辑于星期三\12点16分 RNApol I; Located in nucleolus For pre-rRNA (—18s — 5.8s — 28s — ) 80-85 % of total RNA Two control domains included in cis-factor Trans-factor including Including 4 subunits 1 of TBP (TATA biding protein) 3 of TAF (TBP associate factor) UBF (UPE Binding Factor) SL (Selectivity fa