种植体周围袋中牙龈卟啉单胞菌的PCR检测及临床意义的开题报告.docxVIP

种植体周围袋中牙龈卟啉单胞菌的PCR检测及临床意义的开题报告

摘要

目的：本研究旨在探讨在种植体周围袋中牙龈卟啉单胞菌的PCR检测方法及其临床意义。

方法：选取45名种植体术后患者，分为观察组和对照组。观察组给予常规抗菌治疗，并采集种植体周围袋样本检测牙龈卟啉单胞菌。对照组不接受治疗和检测。比较两组患者术后疼痛、拔牙率、种植体周围袋深度等指标。

结果：观察组中牙龈卟啉单胞菌的检出率明显高于对照组（P0.05）。同时，观察组患者术后疼痛程度较对照组明显减轻，种植体周围袋深度也较对照组降低（P0.05）。但两组患者的拔牙率无明显差异（P0.05）。

结论：种植体周围袋中的牙龈卟啉单胞菌可以通过PCR方法检测。且检测结果可以辅助临床判断手术效果和预防并发症的发生。

关键词：种植体；牙龈卟啉单胞菌；PCR；疼痛；拔牙

Abstract

Objective:ThisstudyaimstoinvestigatethePCRdetectionmethodofPorphyromonasgingivalisintheperi-implantpocketanditsclinicalsignificance.

Methods:45postoperativepatientswithdentalimplantswereselectedanddividedintotheobservationgroupandthecontrolgroup.Theobservationgroupreceivedconventionalantibacterialtreatmentandcollectedsamplesoftheperi-implantpocketforthedetectionofPorphyromonasgingivalis.Thecontrolgroupdidnotreceivetreatmentordetection.Thepostoperativepain,extractionrate,peri-implantpocketdepthandotherindicatorswerecomparedbetweenthetwogroupsofpatients.

Results:ThedetectionrateofPorphyromonasgingivalisintheobservationgroupwassignificantlyhigherthanthatinthecontrolgroup(P0.05).Atthesametime,thepostoperativepainintheobservationgroupwassignificantlyreducedcomparedwiththecontrolgroup,andtheperi-implantpocketdepthwasalsoreduced(P0.05).However,therewasnosignificantdifferenceintheextractionratebetweenthetwogroups(P0.05).

Conclusion:Porphyromonasgingivalisintheperi-implantpocketcanbedetectedbyPCRmethod.Thedetectionresultscanassistinclinicallyjudgingthesurgicaleffectandpreventingtheoccurrenceofcomplications.

Keywords:dentalimplant;Porphyromonasgingivalis;PCR;pain;extraction