凝血障碍和DIC（英文版）课件.pptVIP

血液循环障碍凝血障碍和DIC微循环障碍-Shock心功能障碍HeartFailureIschemia-ReperfusionInjury

CoagulationDisordersandDisseminatedIntravascularCoagulation(DIC)JianzhongShengMD,PhDDepartmentofPathophysiologySchoolofMedicineZhejiangUniversity

NormalHemostasisFirststepinhemostasisisformationofaplateletaggregateAtthemolecularlevelinteractionofcoagulationfactorstakesplaceonthesurfaceofactivatedplateletsTheTissueFactor–FVIIacomplexisthephysiologicalactivatorofnormalhemostasis

HemostasisSubendothelialmatrixNitricoxideEndothelialcell

Initiationofcoagulation

ContactTissue