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CHAPTER

DNA,RNA,andtheFlowof4

GeneticInformation

Familyresemblance,veryevidentinthisphotographoffoursisters,

resultsfromhavinggenesincommon.Genesmustbeexpressed

toexertaneffect,andproteinsregulatesuchexpression.One

suchregulatoryprotein,azinc-fingerprotein(zincionisblue,

proteinisred),isshownboundtoacontrolregionofDNA(black).

[(Left)©NicholasNixon,courtesyFraenkelGallery,SanFrancisco.

(Right)Drawnfrom1AAY.pdb.]

NAandRNAarelonglinearpolymers,callednucleicacids,thatcarry

Dinformationinaformthatcanbepassedfromonegenerationtothenext.OUTLINE

Thesemacromoleculesconsistofalargenumberoflinkednucleotides,each

composedofasugar,aphosphate,andabase.Sugarslinkedbyphosphates4.1ANucleicAcidConsistsofFour

form