Oxaprozin-Standard-Oxaprozinum-Standard-DataSheet-生命科学试剂-MCE.pdf

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Oxaprozin(Standard)

Cat.No.:HY-B0808R

CASNo.:21256-18-8

Synonyms:Oxaprozinum(Standard);Wy21743(Standard)

分⼦式:C₁₈H₁₅NO₃

分⼦量:293.32

作⽤靶点:COX;NF-κB;Akt;IKK;Apoptosis

作⽤通路:Immunology/Inflammation;NF-κB;PI3K/Akt/mTOR;Apoptosis

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

溶解性数据

体外实验DMSO:≥100mg/mL(340.92mM)

*≥meanssoluble,butsaturationunknown.

Mass

Solvent

1mg5mg10mg

Concentration

制备储备液1mM3.4092mL17.0462mL34.0925mL

5mM0.6818mL3.4092mL6.8185mL

10mM0.3409mL1.7046mL3.4092mL

BIOLOGICALACTIVITY

⽣物活性Oxaprozin(Standard)是Oxaprozin的分析标准品。本产品⽤于研究及分析应⽤。Oxaprozin是⼀种⼝服有效

的COX的抑制剂，其对⼈类⾎⼩板COX-1和IL-1刺激的⼈类滑膜细胞COX-2的IC50值分别为2.2和36μ

M。Oxaprozin还能抑制NF-κB的活化。Oxaprozin诱